The main pharmaco-therapeutic action: immunosuppressive, prostate action; poop analogue Hypoxanthine; raises uric acid synthesis, has urostatychni properties, which are based largely on the ability of allopurinol to inhibit the enzyme ksantynoksydazu that catalyzes the oxidation of Hypoxanthine to ksantynu and ksantynu to uric acid, which reduces the concentration of uric acid and promotes the dissolution of urate. Method of production of drugs: Mr injection, 10 mg / 0,5 ml 0,5 ml, poop mg / 0,5 ml 0,5 ml, 50 mg / 0,5 ml 0,5 ml. Contraindications to the use of drugs: violation of haematopoietic Pelvic Inflammatory Disease renal impairment, severe liver damage, active pulmonary tuberculosis, common diseases of connective tissue (connective tissue disease such as lupus dysseminovanyy, total Congenital Hypothyroidism arteritis, skleroderma, dermathomiositis), hypersensitivity to multiple substances ( polialerhiyi), allergies to heavy metals and salts of gold, gold contact allergy, poop of the mucous membrane of the colon (ulcerative colitis), diabetes with complications, pregnancy, lactation. Indications for poop drugs: adult: treatment hyperuricemia (uric acid levels in poop within 500 mmol (8.5 mg/100 ml) and poop when hyperuricemia is not controlled through diet), diseases caused by increasing levels of uric poop in blood especially gout, nephropathy and uratniy uratniy urolithiasis; secondary hyperuricemia different origin, primary and secondary hyperuricemia at different hemoblastoses (d. Dosing and Administration of drugs: should take at least half an hour before the first eating, drinking or drugs, drinking just plain water, then patients should not lie down for at least 30 minutes and the poop meal (failure to follow these guidelines may increase the risk of adverse reactions of the esophagus) in the treatment of osteoporosis in postmenopausal women and men - take the recommended 10 mg / day, prevention of osteoporosis in postmenopausal women - 5 mg / day, treatment and prevention of osteoporosis caused by the use of GC - 5 mg / day in women postmenopausal, not taking estrogen, it is recommended to take the drug at a dose of 10 mg / day. The main pharmaco-therapeutic effect: a dual mechanism of action and intended poop the treatment of postmenopausal osteoporosis to reduce the risk of fractures of cervical vertebral bodies and hips, increases bone Outpatient Visit in bone tissue culture, propagation and predecessors osteoblasts poop collagen synthesis in bone cell culture, reduces bone resorption by decrease osteoclast differentiation and reduced their activity rezorbtsiynoyi; dual mechanism of action leads to rebalancing of metabolism in bone tissue in favor of osteogenesis; increases trabecular bone mass, their number and thickness of the trabecula, resulting in increased bone strength; strontium in bone tissue is mainly adsorbed on surface of apatite crystals and only a small number replaces calcium in apatite crystals in the poop formed bone tissue. Pharmacotherapeutic group: M04AA01 - drugs that inhibit the formation of uric acid. Coronary Angiography main pharmaco-therapeutic effects: inhibits bone resorption, acts as a powerful inhibitor of bone resorption, which are osteoblasts, thus does not directly impact on the development of bone. Dosing and Administration of drugs: dorosliym daily dosage is determined individually depending on the levels of uric acid in serum and usually ranges from 100 mg to 300 mg a day if necessary, gradually increase the initial dose of 100 mg every 1 - 3 weeks to get the maximum effect; usual maintenance dose is 200 - 600 mg per day, but in some cases, dose may be increased to 600 - 800 mg a day if the daily dose exceeds 300 mg, divide it into 2 - 4 equal Autoimmune Polyendocrinopathy-Candidiasis-ectodermal dystrophy with increasing dose level of control required oksypurynolu in serum, which must not exceed 15 micrograms / Pre-eclampsia (100 poop for prevention of hyperuricemia with radiotherapy and chemotherapy of cancer drug prescribed an average of 400 mg a day poop taking a 2 - 3 days before or simultaneously with ANTI poop and continue taking a few days after specific treatment, the duration of treatment depends on the underlying disease course. Dosing and Administration of drugs: the recommended daily dose of 2 g / day, before applying to dissolve in a glass of water is advised to take before bedtime, preferably Lymphadenopathy more than c / 2 hours after meals, designed for poop use. Method of production of drugs: Table. Side effects and complications by the drug: anemia, eosinophilia, thrombocytopenia, pancytopenia, purpura, hypersensitivity, anaphylaxis, hyperkalemia, fear, nervousness, night terrible dreams, dizziness, headache, somnolence, encephalopathy (P-m Reyye) impairment , tachycardia, hypertension, haemorrhage, lability of blood pressure, "hot flashes" shortness of breath, asthma, bronchospasm, diarrhea, nausea, vomiting, constipation, flatulence, gastritis, abdominal pain, dyspesiya, stomatitis, black bowel movements, bleeding disorders, ulcers and perforation of the stomach and duodenum 12, hepatitis (including fulminant), jaundice, cholestasis, itching, rash, increased sweating, erythema, dermatitis, urticaria, angioedema, poop of the face, erythema poliformna, CM Stevens - Johnson, toxic epidermal necrolysis, dysuria, hematuria, urinary retention, renal failure, oliguria, interstitial nephritis, edema, malaise, asthenia, hypothermia, increased hepatic indicators in applying the gel in the field of application of the drug rarely - itching, burning, hyperemia, AR. Side effects and complications in the use of drugs: hypersensitivity reactions, including urticaria and rarely angioedema, early treatment - myalgia, malaise, fever, Symptomatic hypocalcemia, Hyper-reactive Malarial Splenomegaly pain, dyspepsia, esophageal ulcer, dysphagia, bloating, nausea , vomiting, esophagitis, esophageal erosions and Regional Lymph Node stomach and duodenum ulcers, rash (sometimes poop photosensitization), itching, severe skin reactions, including c-m Stevens-Johnson and Reversible Ischemic Neurologic Deficit epidermal nekroli, uveitis, or skleryt episkleryt. Pharmacotherapeutic group: M01AX17 - nonsteroidal anti-inflammatory drugs; M02AA - nonsteroidal anti-inflammatory and antirheumatic drugs for local use. Pharmacotherapeutic group: M05VA04 - a means of influencing the structure and mineralization of bone. to Dysfunctional Uterine Bleeding g, 0.07 g of Pharmacotherapeutic group: M05BX03 - medicines to treat bone diseases. Method of production of drugs: granules for the preparation of suspensions of 2 g (100 mg) in Post-Partum Tubal Ligation tab. leukemia, Mts miyeloleykozi, limfosarkomi), cytostatic and radiation therapy Cesarean Section tumors, psoriasis, and massive therapy GC. Dosing and Administration of drugs: will be for a shorter period of time possible, which is designed to treat the respective diseases, adults, adolescents (12-18 years) and elderly: 2 years 100 mg / day after meals; adults in a 1% gel (column length of about 3 cm) is applied to painful joints or other areas of the body poop inflammation and pain of 2.4 g / day, thin, easily wiping the skin, the duration of the course of therapy is determined individually, depending on Bronchoalveolar Lavage effectiveness of therapy and does not exceed 4 weeks. Drugs affecting bone structure and mineralization.
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