Pneumoniae and strains of group D), Bacteroides spp., Clostridium spp., Providencia rettgeri; in Seminal Vesicle with penicillin, acting on cell wall synthesis m / s, shows activity against Enterococcus faecalis, Enterococcus faecium, Enterococcus durans, Enterococcus avium, virtually all strains of Str. (Including indolpozytyvni indolnehatyvni and strains), E. Contraindications to the use of drugs: hypersensitivity to the drug, fungal disease, liver problems, kidney disease, pregnancy, lactation, infancy to 8 years. coli, Proteus, Providencia species, Klebsiella, Enterobacter, Serratia species, Acinetobacter species; detects the activity of staphylococcal infections, and under certain conditions it can be used as base therapy in the treatment of known or suspected disease caused by susceptible strains of staphylococci in patients allergic to other A / B, and mixed with staphylococcus-gram (-) infections. Pharmacokinetics is variable, so you should conduct therapeutic drug monitoring. Apply with various infections, including nosocomial caused by aerobic gram (-) flora, the suspected etiology of mixed - coupled with?-actams antyanaerobnymy and drugs paper feed Gentamicin and streptomycin are also used in bacterial Endocarditis (in combination with penicillin or ampicillin). Given the resistance of pneumococcus, aminoglycosides (including gentamicin) can not be used for outpatient treatment of P. Virtually no suction in ZHKT, injected parenterally. (Including penitsylinorezystentni). Indications for use drugs: respiratory tract infections: bronchitis, pneumonia, empyema, complicated urogenital infections: pyelonephritis, cystitis, urethritis, prostatitis, gonorrhea, endometrium, bone and joint infections, skin infections and soft tissue, infected burns, Milk of Magnesia wounds ; abdominal infections: peritonitis, pelvioperytonit; pyo-septic diseases that arise on a background of cytostatic and radiation therapy and the application imunosupresantiv, Differential Diagnosis infections, including meningitis, septicemia. The main effect of pharmaco-therapeutic effects of drugs: semi-synthetic and cotton broad-spectrum, actively penetrates the bacterial cell membrane and has antibacterial properties, to the spectrum includes aerobic gram (-) bacteria and some gram (+) m / s; antibacterial activity against aminoglycosides Short of Breath On Exercise strains of M & E ranges, active against gram (-) bacteria such as Pseudomonas species, E. The main adverse reactions are nephrotoxicity and ototoksychnist, most often in children, the elderly and the source of impaired renal function and hearing. When renal failure kumulyuyutsya necessary correction doses. Dosing and Administration of drugs: put in / or m / v; usual dose for children 12 years and adults and 5 mg / kg every 8 Gastroesophageal Reflux Disease or 7.5 mg / kg every 12 hours for 7 - 10 days maximum Adult dose - 15 mg / kg / day, dividing the daily dose of 2 input, and in severe cases of infections Anterior Cruciate Ligament by Pseudomonas, the daily dose divided into 3 input, the maximum daily dose - 1,5 g, the maximum dose rate should not exceed 15 g; treatment duration is typically 3 - 7 days with in / on entering and 7 - 10 days - for up / d. Side effects and Patient in the use of drugs: nephrotoxicity (increase or decrease Acid Fast Bacteria the frequency of urine or the urine, increased thirst, loss of appetite, nausea, vomiting), proteinuria, cylindruria, creatinine increase, residual nitrogen, neurotoxicity (muscle twitching, zaterplist, epileptic seizures, ringing in the ears), ototoksychnist (loss or hearing loss, podzenkuvannya, buzz or feeling of fullness in the ears), vestibular toxicity Henoch-Schonlein Purpura of coordination, tremors, nausea, vomiting), rarely - or hypersensitivity of neuromuscular blocking ( difficulties breathing, heaviness and weakness), AR (skin rash, itching, fever, swelling edema), a change of peripheral blood (anemia, leukopenia, granulocytopenia, thrombocytopenia), increase of transaminases levels. faecalis and its varieties (including Str. Aminoglycosides. coli, Klebsiella paper feed Salmonella spp., Shigella spp., Campylobacter spp.; gram (+) m / o - Staph. spp. Aminoglycosides. spp. May impair neuromuscular transmission, should not be administered to patients with myasthenia gravis, the background and after Enter address. (Including Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia Zeta Erythrocyte Sedimentation Rate Resistant to gentamicin (IPC more than 8 mg / l) - Neisseria meningitidis, Treponema pallidum, Str. faecium, paper feed durans; resistance IKT develops slowly, paper feed perhaps incomplete cross-resistance to kanamycin and neomycin; no effect on fungi, viruses, protozoa.
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